can i take ibuprofen on semaglutide and Diclofenac: Major Drug Interaction Risk What Not to Take With

Nausea (most common, especially during first 1 to 2 weeks of a new dose) Diarrhea or, just as often, constipation Vomiting (less common but more likely at 9 to 12 mg) Reduced appetite, food noise quieting down (this is the goal, not a side effect) Skin sensitivity (dysesthesia): tingling, prickly feeling, or sunburn-like skin

probably because of the differences in the study populations and designs, the study authors explained in their paper for Ophthalmology

Fatty acids (FAs) have therapeutic potential by stimulating GLP-1 secretion

It also slows down gastric emptying, meaning food remains in the stomach longer, which can lead to feeling fuller for a longer period, helping to reduce food intake naturally

It works by mimicking a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels, appetite, and digestion