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Shed's Terms (16.1.2 and elsewhere) list a range of medical conditions that affect eligibility for treatment and for the 120-Day Guarantee, including but not limited to: personal or family history of medullary thyroid carcinoma or MEN 2, type 1 diabetes, active eating disorders, severe gastrointestinal conditions, significant kidney or liver disease, history of pancreatitis, and unmanaged psychiatric conditions

Part of this shift is tied to the natural decline in growth hormone production that occurs with aging

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doi:10.1007/s00125-017-4491-0

Inappropriate medication formulations were ordered in 61.5% of patients (34.7% nonimmediate-release formulations, 25% enteric-coated formulations, and 40.3% both formulations)