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Insurers frequently impose BMI thresholds (typically 30 or higher), require documented diet-and-exercise failures, or demand proof of related conditions like type 2 diabetes or cardiovascular disease

Mulberry leaf extract improves glycaemic response to sucrose in healthy subjects: A randomized, double-blind, placebo-controlled study

With this compound, weight losses of up to 22% are generated in obese individuals [42], and several of the phase III SURPASS trials of patients with T2DM have shown reductions of HbA 1c to values at or below 5.7% (a completely normal value) in more than 50% of the patients, accompanied by weight losses in the order of 12% [43]

10.1016/b978-0-12-813442-9.00007-9 25 HeubergerJ

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