Overview of main clinical studies for MASLD/MASH with GLP-1 receptor agonists and dual or triple agonists targeting glucagon/GIP/GLP-1 receptors Liraglutide Liraglutide, a once-daily GLP-1 receptor agonist with authorized indications for type 2 diabetes and obesity, was evaluated in the LEAN trial (NCT01237119), a phase 2 randomized controlled study enrolling 52 adults with biopsy-proven MASH [22]
Additionally, AI-driven analytics are improving patient monitoring and adherence, especially in digital health platforms that support GLP-1 therapy management
b , Blood glucose profile during ipPTT (pyruvate given at dose of 2g/kg) and ( c ) area under the ipPTT curve
Results: After fully adjusting the data of 6,390 individuals from NHANES between 2015 and 2018, 1,523 (23.83%) of the individuals were identified as having chronic kidney disease (CKD)
Keep a long-term food journal even after symptoms resolve