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95% CI, 1.27-1.87)

In systemic circulation, only about 12% of liraglutide exists in the unbound (free) form, while the remainder is reversibly bound to albumin, effectively serving as a depot that enables sustained pharmacological action

Wegovy and Zepbound accounted for 53.8% of GLP-1 prescriptions

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For researchers comparing options, the Ozempic vs retatrutide comparison and the mazdutide vs retatrutide analysis provide additional context on how retatrutide stacks up against every available alternative