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Next, the supernatant was collected after centrifuging at 1000 rpm for 10 min at 4 C, and then measured at 532 nm with a microplate reader

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Trimethylamine N-oxide ameliorates hepatic damage including reduction of hepatic bile acids and cholesterol in Fxr-null mice

But the FDA flagged a serious adverse event, including a death, associated with an IV ipamorelin infusion (although it wasnt clear whether the peptide directly caused the participant's death)