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Figure 1 Statements Author contributions RC: Writing review & editing, Writing original draft

As noted by Foyer and Halliwell (1976), the chemical reaction between DHA and GSH is much more rapid at higher values of pH (about tenfold faster at pH 8 than pH 7

GLP-1 drugs such as semaglutide are widely used to treat type 2 diabetes and obesity

We call for a reassessment of the role of cell death in disease progression and therapeutic response, with the aim of generating new insights into both basic research and clinical practice

Can glutathione reduce nausea from tirzepatide? No glutathione does not reduce GLP-1-induced nausea and may worsen it if taken during the 2448 hour peak effect window post-injection