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Glucagon is a hormone that causes the liver to release its stored sugar into the bloodstream

Back Lasker Foundation (2024) 'GLP-1-based therapy for obesity'

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doi: 10.1210/en.2007-0340 138 ThammacharoenSKitchanukitwattanaPSuwanapapornPChaiyabutrN

A study published in August 2025 found that lean muscle mass loss via a mouse model was less than previous studies had reported, and also found that a good portion of the And research presented at the European Congress on Obesity (ECO 2025) reported that adults taking GLP-1 drugs were able to retain muscle while losing weight by strength training and eating enough protein