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Clinical studies tested doses ranging from 250mcg to 1mg daily, with 300mcg showing effective fat reduction at the lowest side effect profile
The primary evidence comes from a 2015 study published in Annals of Clinical and Laboratory Science that used a rabbit osteoarthritis model
Lipids 1781 , 643654 (2008)
Capurro S
Special populations, such as post-bariatric surgery patients and those on metformin, may require tailored dosing regimens to ensure adequate vitamin B12 levels
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