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Subsequent reports lowered the concern threshold: the Institute of Medicine set the Tolerable Upper Intake Level (UL) at 100 mg/day for adults based on evidence that neuropathy can appear at chronic intakes above this level [5]
The reason is that were entirely bypassing the pathway those pills work on
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The glucagon-like peptide 1 (GLP-1) analogue, Exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors
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