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( Reference Taes, Delanghe and De Bacquer 7 ) also found no changes in Hcy levels after creatine supplementation at 2 g/d for 28 d in chronic renal patients on haemodialysis, since the subjects were also receiving vitamins B 6 , B 12 and folate
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In studies with mouse models of NAFLD and acute kidney injury (AKI), treatment with ACMSD inhibitors increased the transcription of mitochondrial and -oxidation genes, as well as restoring NAD + levels in the kidney and liver 235
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