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Products labeled "research use only" occupy a regulatory gray area, as the FDA monitors misuse of the designation when sales patterns suggest human consumption

Renal Insufficiency DPP-4 inhibitors have also been examined in placebo-controlled studies in subjects with type 2 diabetes and chronic renal insufficiency, including patients with end-stage renal disease on dialysis (118121)

doi: 10.3389/fendo.2022.809642, 48

availability on the NHS may be limited and patients should discuss current access with their clinician