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Our hypothesis is further supported by the finding that for the sub-group of patients defined a priori as having residual schizophrenia, the effect size was larger, and indeed was largely responsible for the difference in scores between patients and controls

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The angiotensin-converting enzyme (ACE), secreted by lung and kidney, converts ANG I to ANG II, whereas the angiotensin-converting enzyme 2 (ACE2) further cleaves ANG II to ANG (1,7)

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