Neuronale Zeroidlipofuszinose 12 (NCL-12) Einzelanalyse Clinical signs are non-specific and

Clinical signs are non-specific and include abdominal pain

moderate oder schwere generalisierte Schuppung

It is described by cardiac ventricular arrhythmia and sudden cardiac death in the absence of cardiac hypertrophy

It is characterized by degeneration of the cerebellar structures

First clinical symptoms usually appear at 1 or 2 years of age

Neuronale Zeroidlipofuszinose 12 (NCL-12) Einzelanalyse Clinical signs are non-specific andNeuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate