Progressive Retinaatrophie, Early Onset (EO-PRA) - Portugiesischer Wasserhund Rassebestimmung It is synthesized in the

It is synthesized in the liver and secreted into the circulation

Der genetische Defekt ist bei Border Collies relativ häufig

The dog that has both Ayalleles (homozygote Ay/Ay) or one in a combination Ay/aw or Ay/at or Ay/a will be always fawn or sable

Genetic defect is located on chromosome x

Because production of eumelanin is disabled

Progressive Retinaatrophie, Early Onset (EO-PRA) - Portugiesischer Wasserhund Rassebestimmung It is synthesized in theProgressive retinal atrophy (PRA) is an inherited retinal disorder due to degeneration of the rod and cone type of photoreceptor cells in retina. PRA has been identified in a variety of dog breeds with different inheritance patterns. Some breeds are found to have more than one form of PRA. Early onset progressive retinal atrophy (EO PRA) is a new form of PRA with an earlier age of onset (2 3 years). Initial clinical signs include visual deficits